systemic effect - meaning and definition. What is systemic effect
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What (who) is systemic effect - definition

UNINTENDED EFFECT OF DRUGS, WHICH MAY OCCUR FOLLOWING A SINGLE DOSE OR PROLONGED ADMINISTRATION OF A DRUG OR RESULT FROM THE COMBINATION OF DIFFERENT DRUGS
Adverse Drug Reaction; Idiosyncratic reaction; Errors in medication; Adverse drug effect; Adverse Drug Event; Adverse drug events; Drug reaction; Drug toxicity; Systemic effect; Adverse drug reactions; Drug risk; Accidental poisoning; Adverse effect of drug or medicament; Phototoxic drug reaction; Photo-allergic drug reaction; Ichthyosiform reaction to drug; Drug-induced lyell's disease; Pigmentation due to ingested/injected substance; Adverse drug event

Systemic disease         
SYSTEMIC DISEASE IS ONE THAT AFFECTS A NUMBER OF ORGANS AND TISSUES, OR AFFECTS THE BODY AS A WHOLE
Systemic infection; Multisystem disease; Systemic illness; Systemic disorder; Systemic condition; Life-threatening disease; Systemic reaction
A systemic disease is one that affects a number of organs and tissues, or affects the body as a whole.Dorland's Illustrated Medical Dictionary,28th edition (Harcourt Brace & Company).
Systemic scleroderma         
  • Fibroblasts
SCLERODERMA THAT IS CHARACTERIZED BY FIBROSIS (OR HARDENING) OF THE SKIN AND MAJOR ORGANS, AS WELL AS VASCULAR ALTERATIONS, AND AUTOANTIBODIES
Systemic sclerosis; Systemic Sclerosis in Greece; SSc; Progressive systemic sclerosis; Systemic sclerosis (scleroderma); Diffuse cutaneous type systemic sclerosis; Diffuse cutaneous systemic sclerosis
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse.
Sle         
  • epidermal]] cells (antinuclear antibodies are present).
  • Clearance deficiency
  • Germinal centres in a person with SLE and controls (schematic). Red: CD68 in tingible body macrophages; black: TUNEL positive apoptotic cells. 1) Healthy donors with florid germinal centres show giant tingible body macrophages (TBM) containing ingested apoptotic cells and no uningested apoptotic cells outside the TBM. 2) People with follicular lymphoma show small tingible body macrophages (TBM) containing few ingested apoptotic cells however, there are no uningested apoptotic cells outside the TBM. 3) Some with SLE (1) show a lack of TBM and many uningested apoptotic cells decorating the surfaces of spindle-shaped cells, presumably follicular dendritic cells (SLE 1). 4) Some people with SLE show TBM containing few ingested apoptotic cells and many uningested apoptotic cells outside the TBM (SLE 2). However, about 50 % of people with SLE show rather normal germinal centre.
  • date=2009-12-20 }} Last Editorial Review: 2009-01-30</ref>
INFLAMMATION OF CONNECTIVE TISSUE MARKED BY SKIN RASHES, JOINT PAIN AND SWELLING, INFLAMMATION OF THE KIDNEYS AND INFLAMMATION OF THE TISSUE SURROUNDING THE HEART.
Systemic Lupus Erythematosus; Lupus erythematodes; Systemic lupus erythamatosus; Lupus erythematosus, systemic; Lupus erythematosus, discoid; Lupus erythematosus, cutaneous; Systemic lupus erythematosis; Lupus disease; Osler-Libman-Sacks syndrome; Childhood systemic lupus erythematosus; Erythematosus; Lupus (S LE); Systemic lupus erythmatosis; Systemic lupus; Lupus erythematous; Lupus and the brain; Lupus treatment; Systemic lupus erythematosus; Angiolupoid; Lupoid syndrome; Systemic Lupus Erythematosus (SLE); Systemic lupus erythematosus (SLE); Systemic lupus erythemaosus; SLE; Osler–Libman–Sacks syndrome; Disseminated lupus erythematosus
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Wikipedia

Adverse drug reaction

An adverse drug reaction (ADR) is a harmful, unintended result caused by taking medication.: 1.1 Adverse Drug Reaction (ADR)  ADRs may occur following a single dose or prolonged administration of a drug or result from the combination of two or more drugs. The meaning of this term differs from the term "side effect" because side effects can be beneficial as well as detrimental. The study of ADRs is the concern of the field known as pharmacovigilance. An adverse event (AE) refers to any unexpected and inappropriate occurrence at the time a drug is used, whether or not associated with the administration of the drug.: 1.2 Adverse Event (AE)  An ADR is a special type of AE in which a causative relationship can be shown. ADRs are only one type of medication-related harm, as harm can also be caused by omitting to take indicated medications.